OD Optical Diagnostics (ODx) Laboratory UCY  


The lab is coordinating a Horizon 2020 FETOpen project which aims to create a new paradigm of Externally Controllable Molecular Communications for brain tumor theranostics. Read more here.


K. Loizidou, G. Skouroumouni, C. Nikolaou, C. Pitris. “An Automated Breast Micro-Calcification Detection and Classification Technique Using Temporal Subtraction of Mammograms,” IEEE Access, 8:52785-95, 2020. Read the article here.


C. Photiou, C. Pitris, “Comparison of tissue dispersion measurement techniques based on optical coherence tomography,” Journal of biomedical optics, 24(4) 46003, 2019. DOI/10.1117 / 1.JBO.24.4.046003. Read the article here.

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The overarching goal of the laboratory is the introduction of new technologies in clinical applications for the improvement of the diagnostic and therapeutic options of modern health care systems to directly impact patient prognosis and outcome. The research concentrates on two optical technologies which provide complementary, microstructural and biochemical, information.

Optical Coherence Tomography (OCT)

An emerging medical imaging modality which can provide microstructural images of tissue with a micrometer scale resolution. Image resolution improvement and sub-resolution feature information can greatly enhance the diagnostic utility of OCT. Research in this area includes:
  • Improvement of the resolution of OCT systems
  • Scatter size and distribution based diagnostics
  • Specral analysis
  • Dispersion and index of refraction measurements

More information ...

Surface Enhanced Raman Spectroscopy (SERS)

A spectroscopic method which can provide detailed biochemical information of the substances or tissues under investigation. Enhancement of the Raman signal by metal nanosurfaces can make this technique a very sensitive diagnostic tool. Areas of interest include:
  • Classification and antibiogram of bacteria causing Urinary Tract Infections
  • SERS using novel, multi-scale, bio-inspired, nanostructures
  • SERS for food safety

More information ...

Advanced Processing & Classification Methods

A common, horizontal, theme in the laboratory’s research is the processing and analysis of the data collected experimentally. The efficacy of the imaging and spectroscopic methods developed can be significantly enhanced by novel methodologies, including:
  • Quantitative image analysis and feature extraction
  • Advanced classifcation techiques (SVMs, Bioinspired rank order coding, neural networks, etc)
  • Multi-scale, multi-modality, non-uniform data fusion and integration in disease networks

More information ...


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