Useful Links


University of Cyprus















This work has been implemented within the framework of the “Fate, Effect and Removal Potential of Xenobiotics present in Aqueous Matrices (IX-Aqua)”, UPGRADING/DURABLE/0308/07, co-funded by the Republic of Cyprus and the European Regional Development Fund through the Research Promotion Foundation of Cyprus.


List of deliverables (available upon request)

List of scientific publications

1. E. Hapeshi, A. Lambrianides, P. Koutsoftas, E. Kastanos, C. Michael and D. Fatta-Kassinos, "Investigating the fate of the iodinated X-ray contrast media iohexol and diatrizoate during microbial degradation in an MBBR system treating urban wastewater", Environmental Science and Pollution Research, 2013, 20, 6, 3592-3606.

2. I. Michael, E. Hapeshi, V. Osorio, S. Perez, M. Petrovic, A. Zapata, S. Malato, D. Barcelo, D. Fatta-Kassinos, "Solar photocatalytic treatment of trimethoprim in four environmental matrices at a pilot scale: transformation products and ecotoxicity evaluation", Science of the Total Environment, 430, 2012, 167-173.

3. I. Michael, E. Hapeshi, S. Pèrez, M. Petrović, A. Zapata, S. Malato, D. Barceló, D. Fatta-Kassinos, "Light-induced catalytic transformation of ofloxacin by solar Fenton in various water matrices at a pilot plant: Mineralization and characterization of major intermediate products", Science of the Total Environment, 2013, 461-462, 39-48.

4. M.I. Vasquez, M. Garcia-Käufer, E. Hapeshi, J. Menz, K. Kostarelos, D. Fatta-Kassinos, K. Kümmerer, "Chronic ecotoxic effects to Pseudomonas putida and Vibrio fischeri, and cytostatic and genotoxic effects to the hepatoma cell line (HepG2) of ofloxacin photo(cata)lytically treated solutions", Science of the Total Environment, 2013, 450-451, 356-365.

5. D. Fatta-Kassinos, M. Vasquez, K. Kümmerer, "Transformation products of pharmaceuticals in surface waters and wastewater formed during photolysis and advanced oxidation processes – degradation, elucidation of byproducts and assessment of their biological potency", Chemosphere, 85, 2011, 693-709.

6. Z. Frontistis, D. Venieri, E. Hapeshi, C. Drosou, D. Fatta-Kassinos, N.P. Xekoukoulotakis, D. Mantzavinos, "Photocatalytic (UV-A/TiO2) degradation of 17α-ethynylestradiol in environmental matrices: experimental studies and artificial neural network modelling", Journal of Photochemistry and Photobiology A: Chemistry, 240, 2012, 33-41.

7. E. Hapeshi, I. Fotiou, D. Fatta-Kassinos, "Sonophotocatalytic treatment of ofloxacin in secondary treated effluent and elucidation of its transformation products", Chemical Engineering Journal, 2013, 224, 96, 105.


Examples of the research work performed during the Project implementation

  • Determination of the fate and behaviour of xenobiotic compounds during MBR treatment



  • Determination of the fate and behaviour of xenobiotic compounds during MBBR treatment

The overall aim of this study was to fill the aforementioned relevant gaps, by trying to assess the efficacy of the MBBR technology against the removal of IOX and DTZ in urban wastewater. The specific objectives of this study were (i) to investigate the bacterial consortium developed in the MBBR utilizing a molecular approach, (ii) to study the capacity of a pilot MBBR system to remove ICM compounds like IOX and DTZ from urban wastewater, (iii) to characterize their biotransformation products, and (iv) to assess the potential toxicity of the treated effluent.