



Journal Publications
 Harris A.D., Roberton V.H., Huckle D.L., Saxena N., Evans C.J., Murphy K., Hall D.E., Bailey D.M., Mitsis G.D., Edden R.A.E. and R.G. Wise, “Temporal dynamics of lactate concentration in the human brain during acute inspiratory hypoxia,” J Magn Reson Imag (in press).
 Markakis, M.G., Mitsis, G.D., Papavassilopoulos, G.P., Ioannou, P.A. and V.Z. Marmarelis "A Switching Control Strategy for the Attenuation of Blood Glucose Disturbances," Opt Cont Appl Meth 32, 185195, 2011 (pdf).
 Ioannides A.A. and Mitsis G.D. "Do we need to consider nonlinear information flow in corticomuscular interaction?" Clin. Neurophys.121 (3): 272273, 2010 (pdf).
 Mitsis, G. D. , R. Zhang, B.D. Levine, E. Tzanalaridou, D. G. Katritsis and V.Z. Marmarelis "Autonomic Neural Control of Cerebral Hemodynamics: A Nonlinear Study," IEEE Engin. Medic. Biol. Magaz. 28 (6): 5462, 2009 (pdf).
 Mitsis, G.D., Markakis, M.G. and V.Z. Marmarelis, "Nonlinear Modeling of Glucose Metabolism: Comparison of Compartmental with Volterra models," IEEE Trans. Biomed. Eng.56 (10): 23472358, 2009 (pdf).
 Mitsis, G.D., Governo, R.J., Rogers, R. and K.T.S. Pattinson, "The effect of remifentanil upon respiratory variability, evaluated with dynamic modeling," J. Appl. Physiol. 106: 10381049, 2009 (pdf).
 Pattinson, �.�.S., Mitsis, G. D., Harvey, A. K., Jbabdi, S., Dirckx, S., Mayhew, S. D., Rogers, R., Tracey, I. and R. G. Wise "Imaging the Human Brainstem Respiratory Network," Neuroimage 44: 295305, 2009 (pdf).
 Mitsis, G.D., Iannetti, G.D., Smart, T.S., Tracey, I. and R.G. Wise "Regions of Interest analysis in fMRI: how do the Definition Criteria influence the inferred Result?," Neuroimage 40: 121132, 2008 (pdf) .
 Mitsis, G.D., French, A.S., Hoger, U., Courellis, S. and V Z. Marmarelis. "Principal Dynamic Mode Analysis of Action Potential Firing in a Spider Mechanoreceptor," Biol. Cybern. 96: 113127, 2007 (pdf).
 Mitsis, G.D., Zhang, R., Levine, B.D. and V.Z. Marmarelis. "Cerebral Hemodynamics during Orthostatic Stress assessed by Nonlinear Modeling," J. Appl. Physiol. 101: 354366, 2006 (pdf).
 Mitsis, G.D., Ainslie, P.N., Poulin, M.J., Robbins P.A. and V. Z. Marmarelis. "Nonlinear Modeling of the Dynamic Effects of Arterial Pressure and Blood Gas variations on Cerebral Blood Flow in Healthy Humans" Adv. Exp. Med. Biol. 551: 259265, 2004 (pdf).
 Mitsis, G.D., Poulin, M.J., Robbins, P.A. and V.Z. Marmarelis. "Nonlinear Modeling of the Dynamic Effects of Arterial Pressure and CO2 Variations on Cerebral Blood Flow in Healthy Humans," IEEE Trans. Biomed. Eng. 51: 19321943, 2004 (pdf).
 Mitsis, G.D., Zhang, R., Levine, B.D. and V.Z. Marmarelis. "Modeling of Nonlinear Systems with Fast and Slow Dynamics. II. Application to Cerebral Autoregulation in Humans," Ann. Biomed. Eng. 30: 555565, 2002 (pdf).
 Mitsis, G.D. and V.Z. Marmarelis. "Modeling of Nonlinear Systems with Fast and Slow Dynamics. I. Methodology," Ann. Biomed. Eng. 30: 272281, 2002 (pdf).
 Nikita, K.S., Mitsis, G.D. and N.K. Uzunoglu. "Analysis of Focusing of Pulsed Baseband Signals inside a Layered Tissue Medium," IEEE Trans. Microw. Theory Techn. 48: 3039, 2000 (pdf).
Book chapters
 Mitsis, G.D., Markakis, M.G and V.Z. Marmarelis "Datadriven Modeling of Dynamic InsulinGlucose Interactions: Comparison of Volterra Models with Compartmental Models and Application to Resting InsulinGlucose Fluctuations in a Fasting Dog," in Springer Lecture Notes in Mathematics, Mathematical Biosciences Subseries, Springer (in press).
 Markakis, M.G., Mitsis, G.D., Papavassilopoulos, G.P. and V.Z. Marmarelis "Nonparametric modeling and modelbased control of the insulinglucose System," in Recent Advances in Biomedical Engineering, edited by D. Campolo, pp. 120, InTech, Vienna, Austria (pdf).
 Mitsis, G.D., Zhang, R., Levine, B.D. and V. Z. Marmarelis "Nonlinear Physiological Systems Identification: Application to Cerebral Hemodynamics under Orthostatic Stress," Mathematical Methods in Scattering Theory and Biomedical Engineering, Proceedings of the 7th International Workshop, edited by D.I. Fotiadis, World Scientific, pp. 362369, 2006
Conference proceedings and abstracts
 Hadjiandreou M.M. and G.D. Mitsis "Modelbased control of cancer progression subject to drugresistance” 51st IEEE Conference on Decision and Control, Maui HI, December 2012 (submitted).
 Hadjiandreou M.M., Gkoutos G.V., Conejeros R. and G.D. Mitsis “Investigation of cancer progression via mathematical modelling and optimal control” 11th International Symposium on Process Systems Engineering (PSE2012), Singapore, July 2012 (accepted).
 Prokopiou, P., Pattinson, K.T.S., Wise, R.G. and G.D. Mitsis “Identification of the regional variability of the brain hemodynamic response to spontaneous and stepinduced CO2 changes using function expansions,” 16th IFAC Symposium on System Identification, Brussels, Belgium, July 2012 (accepted).
 Hadjiandreou M.M. and G.D. Mitsis “Towards tumor growth control subject to reduced toxicity,” American Control Conference (ACC2012), Montreal, Canada, June 2012 (accepted).
 Hadjiandreou M.M. and G.D. Mitsis “Modelbased treatment of colon cancer in mice,” European Symposium on Computer Aided Process Engineering (ESCAPE22), London, UK, June 2012 (accepted).
 Markou M.M., Poulin M.J. and G.D. Mitsis “Nonstationary analysis of cerebral hemodynamics using adaptive multipleinput nonlinear models”, Proc. 50th IEEE Conference on Decision and Control and European Control Conference, pp. 5768 – 5773, Orlando FL, December 2011 (pdf).
 Mitsis G.D. and M.M. Markou “Recursive least squares estimation of nonlinear multipleinput systems using orthonormal function expansions,” 33rd Ann. Intern. Conf. IEEE EMBS, pp. 37283731, Boston MA, September 2011 (pdf).
 Mitsis G.D. “The VolterraWiener approach in neuronal modeling”, 33rd Ann. Intern. Conf. IEEE EMBS, pp. 59125915, Boston MA, September 2011 (invited  pdf).
 Mitsis G.D. “Datadriven modeling of cerebral hemodynamics,” Cerebral haemodynamics: measurement & management IPEM meeting, London, UK, June 2011 (invited).
 Mitsis G.D. and G.D. Iannetti "Assessment of nonlinear interactions in eventrelated potentials (ERPs) elicited by stimuli presented at short interstimulus intervals" Proc. 32nd Ann. Intern. Conf. IEEE EMBS, pp. 4834  4837, Buenos Aires, Argentina, August 2010 (pdf).
 Mitsis, G.D. and S. Jbabdi "Bayesian estimation of dynamic systems function expansions," Proc. 4th Intern. Symp. Communic. Cont. Signal Proc. (ISCCSP 2010), Limassol, Cyrpus, March 2010 (pdf).
 Mitsis, G.D. "Nonlinear, datadriven modeling of cardiovascular and respiratory control mechanisms," Proc. 9th International Conference on Information Technology and Applications in Biomedicine (ITAB 2009), pp. 14, Larnaca, Cyprus, November 2009 (pdf).
 Mitsis, G.D. "Nonlinear, datadriven modeling of cardiorespiratory control mechanisms," Proc. 31st Ann. Intern. Conf. IEEE EMBS, pp. 43604366, Minneapolis, MN, August 2009 (invited session  pdf).
 Mitsis, G.D., Governo, R.J., Rogers, R. and Pattinson, K.T.S. "The effect of remifentanil on respiratory control, assessed from resting physiological variability," Biosignal Interpretation Conference, pp. 100103, New Haven, CT, June 2009 (pdf).
 Mitsis, G.D., Harvey, A. K., Dirckx, S., Mayhew, S. D., Rogers, R., Tracey, I., Wise, R.G. and K.T.S. Pattinson "Modeling of regional dynamic CO2 reactivity in respiratory related brain areas using BOLD fMRI," Proc. 8th Intern. Conf. Bioinform. Bioengin. (BIBE), pp. 15, Athens, Greece, October 2008 (pdf).
 Mitsis, G.D. and S. Jbabdi "Bayesian model order selection for nonlinear systems function expansions," Proc. 30th Ann. Intern. Conf. IEEE EMBS, pp. 21652168, Vancouver, BC, Canada, August 2008 (pdf).
 Markakis, M.G., Mitsis, G.D., Papavassilopoulos, G.P. and V.Z. Marmarelis "Model Predictive Control of Blood Glucose in Type 1 Diabetics: the Principal Dynamic Modes approach," 30th Ann. Intern. Conf. IEEE EMBS, pp. 54665469, Vancouver, BC, Canada, August 2008 (pdf).
 Markakis, M.G., Mitsis, G.D. and V.Z. Marmarelis "Computational Study of an Augmented Minimal Model for Glycaemia Control," 30th Ann. Intern. Conf. IEEE EMBS, pp. 54455448, Vancouver, BC, Canada, August 2008 (pdf).
 Pattinson, �.�.S., Mitsis, G. D., Harvey, A. K., Jbabdi, S., Dirckx, S., Mayhew, S. D., Rogers, R., Tracey, I. and R. G. Wise "Imaging the human brainstem respiratory network," Intern. Conf. Amer. Thoracic Soc., Toronto, Canada, May 2008.
 G. D.� Mitsis, R. Zhang, B.D. Levine, E. Tzanalaridou, D. G. Katritsis and V.Z. Marmarelis "Autonomic Neural Control of Cerebral Hemodynamics: A Nonlinear Study," 5th Conf. Europ. Study Group Cardiov. Oscill., Parma, Italy, April 2008 (pdf).
 Pattinson, K.T.S., Governo, R.J., Rogers, R., Russell, E.C., Tracey, I., Wise, R.G. and G.D. Mitsis. "Opioids increase respiratory variability in conscious humans," Annual Congress of the Association of Anaesthetists of Great Britain & Ireland, Dublin, Ireland, September 2007.
 Mitsis, G.D., Debert, C.T., Hajo, M.I., Marmarelis, V.Z. and M. J. Poulin "Nonlinear, multipleinput modeling of cerebral hemodynamics during baseline and hypercapnia in young and postmenopausal women," Proc. 29th Ann. Intern. Conf. IEEE EMBS, pp. 28552858,Lyon, France, August 2007 (pdf).
 Mitsis, G.D. and V.Z. Marmarelis, "Nonlinear modeling of glucose metabolism: comparison of parametric vs. nonparametric methods," Proc. 29th Ann. Intern. Conf. IEEE EMBS, pp. 59675970, Lyon, France, August 2007 (pdf).
 Mitsis, G.D., Pattinson, �.�.,� Harvey, A. K., Dirckx, S., Mayhew, S. D., Hoar, H., Rogers, R., Tracey, I. and R. G. Wise "Modeling of dynamic CO2 reactivity in the human brainstem using BOLD FMRI," 13th Ann. Meet. Organ. Hum. Brain Mapp., Chicago, IL, June 2007.
 Mitsis, G.D., Iannetti, G.D., Smart, T.S., Tracey, I. and R.G. Wise "Regions of interest analysis: Insights from a pharmacological fMRI experiment," 13th Ann. Meet. Organ. Hum. Brain Mapp., Chicago, IL, June 2007.
 Pattinson, �.�.,� Mitsis, G. D., Harvey, A. K., Dirckx, S., Mayhew, S. D., Hoar, H., Rogers, R., Tracey, I. and R. G. Wise "Mapping BOLD Sensitivity to CO2 in the Human Brainstem," Joint Ann. Meet. Intern. Soc. Magn. Reson. Imag. (ISMRM)ESMRMB, Berlin, Germany, May 2007.
 Pattinson, �.�.,� Mitsis, G. D., Harvey, A. K., Dirckx, S., Mayhew, S. D., Hoar, H., Rogers, R., Tracey, I. and R. G. Wise, "The BOLD FMRI response to Spontaneous Fluctuations in CO2, Evaluated in the Human Brainstem," Joint Ann. Meet. Intern. Soc. Magn. Reson. Imag. (ISMRM)ESMRMB, Berlin, Germany, May 2007.
 Mitsis, G.D., Debert, C.T., Hajo, M.I., Marmarelis, V.Z. and M. J. Poulin "Nonlinear, multipleinput modeling of cerebral hemodynamics during baseline and hypercapnia in young and postmenopausal women," 15th Intern. Hypoxia Symp., Lake Louise, Alberta, Canada, February 2007.
 Mitsis, G.D., French, A.S., Hoger, U, Courellis, S. and V Z. Marmarelis "Nonlinear Dynamic Modeling of Action Potential Encoding in two Types of Spider Mechanoreceptors," Proc. 3rd Europ. Med. Biol. Eng. Conf (EMBEC 05), IFBME Proc. 11(1), pp. 10611065, Prague, Czech Republic, November 2005 (pdf).
 Mitsis, G.D., Zhang, R., Levine, B.D. and V. Z. Marmarelis "Nonlinear Physiological Systems Identification: Application to Cerebral Hemodynamics under Orthostatic Stress," Proc. 7th Intern. Worksh. Math. Meth. Scatter. Theory Biomed. Engin., Nymphaio, Greece, September 2005.
 Mitsis, G.D., Zhang, R., Levine, B.D. and V. Z. Marmarelis "Cerebral Hemodynamics under Orthostatic Stress: Assessment by Nonlinear Modeling," 35th Intern. Cong. Physiol. Sciences (IUPS), San Diego, CA, April 2005.
 Mitsis, G.D., Courellis, S., French, A.S. and V Z. Marmarelis "Principal Dynamic Mode Analysis of a Spider Mechanoreceptor Action Potentials," Proc. 25th Anniv. Conf. IEEE EMBS, Cancun, Mexico, pp. 20512054, September 2003 (pdf).
 Mitsis, G.D., Mahalingam, A., Zhang, R., Levine, B.D. and V. Z. Marmarelis "Nonlinear Analysis of Dynamic Cerebral Autoregulation in Humans under Orthostatic Stress," Proc. 25th Anniv. Conf. IEEE EMBS, Cancun, Mexico, pp. 398401, September 2003 (pdf).
 Mitsis, G.D., Ainslie, P.N., Poulin, M.J., Robbins P.A. and V. Z. Marmarelis "Nonlinear Modeling of the Dynamic Effects of Arterial Pressure and Blood Gas variations on Cerebral Blood Flow in Healthy Humans," 9th Oxford Conf. Postgen. Persp. Model. Contr. Breath., Paris, France, September 2003.
 Marmarelis, V.Z., Mitsis, G.D., Huecking, K. and R.N. Bergman. "Nonlinear Modeling of the InsulinGlucose Relationship in Dogs," Proc. 2nd J. Meet. IEEE EMBSBMES, Houston, TX, vol. 1: 224225, October 2002 (pdf).
 Mitsis, G.D., Poulin, M.J., Robbins, P.A. and V.Z. Marmarelis. "Nonlinear Multivariate Analysis of Dynamic Cerebral Blood Flow Regulation in Humans," Proc. 2nd J. Meet. IEEE EMBSBMES, Houston, TX, vol. 2: 13411342, October 2002 (pdf).
 Mitsis, G.D. and V.Z. Marmarelis. "Nonlinear Modeling of Physiological Systems with multiple inputs", Proc. 2nd J. Meet. IEEE EMBSBMES, Houston, TX, vol. 1: pp. 2122, October 2002 (pdf).
 Marmarelis, V.Z. and G.D. Mitsis. "Nonparametric Modeling of the GlucoseInsulin System", Ann. Meet. BMES, Seattle, WA, October 2000.
 Mitsis, G.D., Zhang, R., Levine, B.D. and V.Z. Marmarelis "Nonlinear Modeling of Dynamic Cerebral Autoregulation in Humans",Ann. Meet. BMES, Seattle, WA, October 2000.
 Mitsis, G.D. and V.Z. Marmarelis "Modeling of Nonlinear Systems with Fast and Slow Dynamics using LaguerreVolterra Networks",Ann. Meet. BMES, Seattle, WA, October 2000.
 Nikita, K.S., Mitsis, G.D. and N.K. Uzunoglu. "Generation of a Focused Electromagnetic Field Inside a Tissue Medium by Using Short Baseband Pulses", Proc. 20th Ann. Intern. Conf. IEEE EMBS, vol. 20 (6): 32573260, 1998 (pdf).
 Nikita, K.S. and G.D. Mitsis, "Analysis of coupling phenomena in a TEM concentric array of applicators radiating into a layered biological tissue model," Proc. 1998 APS Intern. Symp., 19841987, 1998 (pdf).
 Nikita, K.S., Mitsis, G.D. and N.K. Uzunoglu, "Investigation of Focusing of Short Baseband Pulses inside Biological Tissue Media Using a TEM Concentric Array of Applicators", Proc. Intern. Symp. Electrom. Theory, URSI, 414416, Thessaloniki, Greece, May 1998.




